Scientific program of the Department:
1. The molecular basis of secondary immunodeficiencies and methods for their correction.
2. Molecular mechanisms of damage to biological membranes.
3. Synthesis of biologically active compounds based on complexes of biogenic elements with ligands.
The staff of the department widely publish the results of their scientific work in leading peer-reviewed scientific journals and collections abroad (SCOPUS, IF, RSCI), including in highly rated domestic scientific journals (VAK RUz).
Employees of the department participate and make presentations at the Institute of Tashkent Pediatric Medical Institute, at national and international conferences.
Protection Dissertations
Over the past period, the applicant Rasulova Mohidil Tursunalievna in 2020 defended her thesis under the supervision of Dr. Sc., Professor Yuldashev N.M. on the topic “The relationship between the monooxygenase system of the liver and the thyroid status of the body (experimental study)” under the Scientific Council for awarding scientific degrees DSс 03/30. 2019.B.01.13 at the Institute of Biophysics and Biochemistry of the National University of Uzbekistan. Specialty Code 03.00.01 – Biochemistry.
Cooperation Department
In scientific work, the department works closely with the Department of Biochemistry of TMA, the Department of Clinical and Laboratory Diagnostics of TashIUV, the Institute of Bioorganic Chemistry of the Academy of Sciences of Uzbekistan named after Academician A.S. Sadykova, with the Institute of Biochemical Physics RAS (Moscow), the Department of Biochemistry of the Urgen Branch of TMA, the Department of Biochemistry of the Nukus Branch of TashPMI.
Membership in scientific organizations and editorial boards
Currently, members of the department are academician Saatov T.S. is a member of the Specialized Council 03.00.01- Biochemistry, Biophysics and Radiobiology at the Institute of Bioorganic Chemistry.
Professor Yuldashev N.M. – Member of the Academic Council, Doctor of Technical Sciences 07.27.2017. Tib. 30.03 according to TTA; Member of the Academic Council 12/29/2018 .01.01.13 at the Institute of Biophysics and Biochemistry of the National University of Uzbekistan; member of the Scientific and Technical Council of the medical section; Member of the Scientific and Technical Council for Biology; Chairman of the Biochemical Monothematic Council; Member of the scientific seminar “Pathological physiology” at the Academic Council DN.27.07.2017. Tib.30.03; DSc. 27.07.2017.Tib.30.03; participant in the scientific seminar “Biochemistry” at the Academic Council; Member of the Board of Trustees of TashPMI.
Ph.D. Khaibullina Z.R. He is the chairman of the problem committee of the Medical and Biological Faculty of Tashkent Pediatric Medical Institute. DSc. 27.06.2017. Tib. 29.01. 14.00.01 – Obstetrics and Gynecology, 14.00.09 – Pediatrics, 14.00.11 – Secretary of the Scientific Seminar on Dermatology and Venereology at the Academic Council.
Publications 2019-2020
| № | Title of works | Printed | Edition | Authors |
| 1 | Functional and metabolic state of the monooxygenase system of the liver in experimental hypothyroidism | Article | Scientific Bulletin of Namangan State University, No. 7, 2019, P.73-79 | Rasulova M.T., Nishantaev M.K., Yuldashev N.M. |
| 2 | The thyroid status of the organism in the inhibition of the monooxygenase system of the liver in the experiment | Article | Scientific Bulletin of Namangan State University, No. 2, 2019, P.116-123 | Rasulova M.T., Yuldashev N.M. |
| 3 | Functional and metabolic state of the monooxygenase system of the liver in experimental hypo- and hyperthyroidism | Article | Scientific-abstract, spiritual and educational journal “New Day in Medicine”, No. 4 (28), 2019, P. 414-418 | Rasulova M.T., Nishantaev M.K., Yuldashev N.M. |
| 4 | Synthesis of some substituted analogues of natural flavones and chalcones | Article | The scientific journal Spirit-time, Vol. 1. No. 10 (22), “NG Verlag”, Berlin, 2019. P. 27-29. | Ismailova G.O., Karimova Sh.F., Avazov X.B. |
| 5 | Сonformation of the structure of hydroxyl-containing chalcons with 1,5-benzodioxepane fragment | Article | International Journal Of Professional Science (IJPS), №2 Russia, Nizhny Novgorod, Scientific public organization “Professional science”, 2020, P. 44-47. | Ismailova G. O., Rahmanova M. U. Karimova M. M. |
| 6 | Synthesis of Some Substituted Analogues of Natural Flavones and Chalcones | Article | International Journal of Psychosocial Rehabilitation, Vol. 24, Special Issue 1, 2020, Р. 840-844. ISSN: 1475-7192 DOI: 10.37200/IJPR/ V24SP1/PR201226 London, United Kingdom | Gulzira Ismailova, Shakhnoza Abzalova, Zulfiya Ikramova, Bakhromkhodja Aykhodjaev, Sabirdjan Arifdjanov |
| 7 | “Chemical structure – biological activity” of some synthesized derivatives of chalcones | Article | Vestnik magazine of the Karakalpak branch of the Academy of Sciences of the Republic of Uzbekistan. No. 1. Nukus “Ilim”, 2020. P. 41-45. | Ismailova G.O., Yuldashev N.M., Uzakbergenova Z.D. |
| 8 | The placenta permeability for 14C-thyroxine at different stages of pregnancy in animals | Article | Scientific and practical journal “Pediatrics”, No. 1. 2020. P.132-136. | Karimova Sh.F., Yuldashev N.M., Ismailova G.O., Mirmahmudova S.I. |
| 9 | Endocrine system in the aspect of medical and biological chemistry | Article | iScience “Actual challenges of modern science”, Pereyaslav (Ukraine), No. 3 (47), part 1. 2020, P.14-16. | Ziyamutdinova Z.K., Mirsobitdinova M.M., Khatamova Z.Z., Solieva K.S., Yunusova K.B. |
Textbooks 2019-2020
| № | Job title | Edition | Authors |
| 1 | Medical biochemistry (for students of a higher medical institute) | “O’zkitobsavdonashriyoti” LLC, Tashkent-2020, 580 pp. (in Russian language) | Sabirova R.A., Yuldashev N.M., Inoyatova F.Kh., Kulmanova M.U. |
| 2 | Tibbiy biokimyo (tibbiyot oliy Kuv yurtlari talabalari uchun) | “O’zkitobsavdonashriyoti” LLC, Toshkent-2020, 632 pp. (in Uzbek language) | Sabirova R.A., Yuldashev N.M., Inoyatova F.Kh., Kulmanova M.U. |
Conferences 2019-2020
Employees of the department participate and make presentations at national and international conferences.
| № | Title of works | Printed | Edition | Authors |
| 1 | Biochemical features with cholestatic liver condition | Thesis | Republican materials 12th interdisciplinary remote online conferences on the theme “Scientific and practical research in Uzbekistan “part-4, Р. 183. | Rasulova M.T., Nishantaev M.K., Yuldashev N.M. |
| 2 | Influence of the state of the thyroid gland of a lactating rat on the activity of enzymes in the liver and digestive system of newborn rats | Thesis | Collection of scientific papers of the II International scientific and practical on-line conference “Actual issues of medical science in the XXI century” TashGosStomInstitut, Uzbekistan, December 15, 2019. P. 99-100 | Karimova Sh.F., Ismailova G.O., Tagaimuradova Z.F. |
| 3 | Synthesis of natural coumarine with 1,6-benzodioxocine fragment | Thesis | International Online Conference “Health-saving activities of an educational institution: effective techniques and methods” https://interactive-plus.ru/article/530018/discussion_platform Center for Scientific Cooperation “Interactive Plus” 01/22/2020, P.1-3. Russia, Cheboksary | Ismailova G.O., Abdikulova U.A., Ilyasova Z.E. |
| 4 | The study of the synthetic model of 3-hetarylcoumarin with a 1,4-benzodioxane fragment using the mass spectrum | Thesis | Materials of the scientific conference “PROBLEMS OF BIOPHYSICS AND BIOCHEMISTRY – 2020”. Institute of Biophysics and Biochemistry and Faculty of Biology at the National University of Uzbekistan named after Mirzo Ulugbek; May 22, 2020, P. 86. | Ismailova G.O., Ziyamutdinova Z.K., Azizova N.M. |
| 5 | Membrane-stabilizing effect of liposomes in liver pathology | Thesis | There too. P. 69 | Ziyamutdinova Z.K., Ismailova G.O., Karimova Sh. F. |
| 6 | Biochemical markers of subclinical inflammation at patients with coronary atherosclerosis and metabolic syndrome | Thesis | There too. P. 3 | Abdullaeva S.D., Khaybullina Z.R., Nishantaev M.K. |
Student Scientific Society of the Department
The department operates the Student Scientific Society (SSS) and the circle “Young Biochemist”. Participants of SSS are actively engaged in scientific work, publish abstracts of work at the Institute of Tashkent Pediatric Medical Institute, at national and international conferences of SSS. Areas of scientific activity of the Young Biochemist club: free-radical processes in the body for various diseases.
Publications of aids to 2019-2020
| № | Title of works | Printed | Edition | Scientific supervisor | Surname students |
| 1 | Antituberculosis activity of synthesized 3-heteroaryl-4Н-coumarins | Thesis | Collection of articles on materials International scientific-practical conference “Actual issues of modern science: theory, methodology, practice, innovation ” Part 2.17 January 2020, Publishing House “Research Center Herald of Science”. Russia, Ufa. P. 137-141. | Ismailova G.O. | Azamov R.T., Butaboeva S.Sh. 205-medical business |
| The synthesized flavone cytoprotective activity | Thesis | “Scientific works of gifted youth and 21st century medicine”. Materials Republican 48 scientific and practical online video conference of student scientific society dedicated to the “Year of the development of science, education and digital Economics ”. Tashkent-2020, May 20, TashPMI, P. 374. | Ismailova G.O. | Abdijafarov A.T. 203-medical ped | |
| The biological activity of the synthesized 3-amino, 6-fluoro-3′,4′-ethylenedioxyflavone | Thesis | There too. P. 374-375 | Ismailova G.O. | Abdikulova U.A. 205-medical business | |
| The effect of thyroidectomy and hyperthyroidism on the activity of Ca2+/H2+ antiporter in mitochondria of rat liver | Thesis | There too. P. 387. | Karimova Sh.F. | Goziev N. 210-1 ped | |
| The effect of changes in the functional state of the thyroid gland of a lactating female on metabolic processes in the body of newborn rat pups | Thesis | There too. P. 410. | Karimova Sh.F. | Shodiev I. 209-2 ped | |
| Apoptoz va uning biologik ahamiyati | Thesis | There too. P. 390 | Karimova Sh.F. | Komilzhonov Z.R. 210-1 ped. | |
| The importance of liposomes for membrane stabilization | Thesis | There too. P. 393. | Ziyamutdinova Z.K. | Mirzakulova L. 212-medical ped | |
| Impaired carbohydrate metabolism in the liver | Thesis | There too. P. 409. | Ziyamutdinova Z.K. | Holova N. 212-1 ped | |
| Аpaptoz mexanizmlarining organizmdagi ahamiyati | Thesis | There too. P. 399. | Azizova N.M. | Radjabmuxamedova S. 202-medical ped | |
| Еksperimental giperxolesterinemiya rivojlanishida qon zadobidagi yogʻ kislotalari tarkibining oʻzgarishi | Thesis | There too. P. 383. | Azizova N.M. | Asqarov M.T. 201-medical business | |
| Siydik kislata hosil bo`lish mexanizmi va uning ahamiyati. | Thesis | There too. P. 408. | Azizova N.M. | Xolmurodova M. 202-medical ped |
Circle leader: ass. Suleymanova G.G.
• Publishing of student works in scientific materials (see: Downloads)